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1996-02-27
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Document 0463
DOCN M9630463
TI Opioid use in HIV patients with neurological changes.
DT 9603
AU Paice JA; Pugliese JC; Fitzpatrick JE; Rush-Presbyterian-St. Luke's
Medical Center, Chicago, IL, USA.
SO J Assoc Nurses AIDS Care. 1995 Jul-Aug;6(4):28-36. Unique Identifier :
AIDSLINE MED/96054500
AB The neurological changes that are common in the HIV population may
complicate the use of analgesics, particularly opioids. These changes,
in combination with care providers' fear of opioids, often lead to the
inappropriate use of antagonists, such as naloxone. Used injudiciously,
naloxone can lead to withdrawal syndrome, return of severe pain, and
other adverse effects. The authors describe the many disease and
treatment-related causes for pain in patients with HIV disease, as well
as common neurologic conditions that alter cognition and complicate the
use of opioids. A case study is included to illustrate the dangers of
inappropriate naloxone use.
DE Adult Attitude of Health Personnel Case Report Female Human HIV
Infections/*COMPLICATIONS Naloxone/ADVERSE EFFECTS
Narcotics/*THERAPEUTIC USE Nervous System Diseases/*ETIOLOGY
Pain/*DRUG THERAPY/ETIOLOGY Pain Measurement JOURNAL ARTICLE REVIEW
REVIEW LITERATURE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).